Great Dane Mixes – Is One of These Giant Hybrids Is Right For You?

Are you ready to meet some head-turning Great Dane mixes?

The Great Dane is an unmistakable purebred dog breed, but what about when they make puppies with a different pedigree?

In this article, we’ll learn more about some of the most popular Great Dane mixes!

The Great Dane

For many Great Dane fans, there is no other dog breed than the Great Dane.

While the Great Dane may look particularly majestic and imposing on the outside, underneath you’ll find a playful pup who just wants to love and be loved!

Size, Weight, and Height

Some refer to the Great Dane as the “gentle giant,” which makes sense given this pup can easily top three feet and weigh 190+ pounds.

Just to prove it, the biggest living Great Dane, Freddy, weighs in at 200 pounds and stands nearly 3 foot 5 inches feet tall!

His favorite snacks are whole roast chickens and sofas — Freddy and his sister have reportedly polished off 26 of them to date!

Personality and Temperament

Great Danes are very exuberant in puppyhood and they crave lifelong activity, playtime, and affection.

But because this dog breed is so enormous, early and ongoing training and socialization is key to fostering safe play and family time for all.

Coat grooming and shedding

The Great Dane has a short, smooth-hair coat that will shed lightly but on an ongoing basis.

Health and Longevity

The Great Dane typically lives 7 to 10 years.

Great Danes can inherit certain known genetic health issues including

• hip dysplasia
• panosteitis
• hypertrophic osteodystrophy
• Wobbler’s syndrome
• cancer, heart issues
• thyroid disorders
• cataracts.

But the number one danger to Great Danes is a condition called gastric torsion, or bloat.

So, if you do own a Great Dane, there is a simple preventative veterinary procedure you may want to consider.

Great Dane Mixes

Hybrid dog breeding — crossing two different purebred dog breeds — is not an entirely new area of focus for canine breeders.

But as certain known purebred dog genetic health concerns become increasingly pressing, hybrid breeding has offered one avenue to strengthen the gene pool for future generations.

Despite the possibility of better health for future generations of companion canines, hybrid breeding continues to be controversial even today.

The important thing to remember when choosing a mixed breed dog is that it is impossible to predict how much each purebred parent will influence the traits of a puppy.

From coat type to temperament, height and weight to health issues, choosing a puppy bred from early hybrid generations can be of a gamble!

However, later hybrid generations typically deliver more uniformity between puppies in a litter and from litter to litter.

Therefore, if you have specific needs, interests or constraints (such as your puppy’s adult size or coat type), working with a later generation hybrid breeder is definitely the way to go!

List of Great Dane Mixes

Are you reading this article for information about a specific Great Dane mix breed dog?

Use this handy list to head straight to the pup you want to learn more about – can you guess what the other breed is in each mix?

• American Bull Dane
• American Foxydane
• Great Danebull
• Plush Danois
• Great Dasenji
• Great Hound
• Boxane
• Doberdane
• Great Shepherd
• Great Retriever
• Pyredane
• Greater Swissdane
• Irish Dane
• Labradane
• Daneiff
• Great Danoodle
• Weilerdane
• Saint Dane
• Great Danesky
• Weimar Dane

Let’s see how you did!

American Bulldog Great Dane Mix

Also known as: an American Bull Dane

The American Bull Dane has one American Bulldog parent and one Great Dane parent. So this is certainly going to be a strong and powerful dog.

This pup will likely weigh between 40 and 190 lbs with a life expectancy of 7 to 10 years.

Expect some year-round shedding with this dog’s short, smooth coat.

Bulldogs are a brachycephalic (flat-faced) dog breed, which means their puppies can inherit respiratory, overheating, eating, and eye issues.

American Foxhound Great Dane Mix

Also known as: an American Foxydane

The American Foxydane is what you get by crossing an American Foxhound with a Great Dane.

This dog’s adult weight will weigh between 60 and 190 lbs with a life expectancy of 7 to 13 years.

Their coat will be simple to care for but may shed lightly year-round.

Also important to note, the American Foxydane will need lots of activity to stay healthy and happy!

Pitbull Terrier Great Dane Mix

Also known as: a Great Danebull

A Great Danebull is a cross between an American Pitbull Terrier and a Great Dane.

This dog may weigh anywhere from 35 to 190 pounds with a life expectancy of 7 to 15 years.

Be aware that they will probably shed year-round.

The Pitbull has lately gotten a bad rap as a breed. However, a well-bred Pitbull dog actually has a similar disposition to the Great Dane — loving, affectionate, protective, and very people-oriented.

Anatolian Shepherd Great Dane Mix

Also known as: a Plush Danois

The Plush Danois is the name given to a puppy with one Anatolian Shepherd parent and one Great Dane parent.

Like the Great Dane, the Anatolian Shepherd is a sizable pooch, so expect your dog to weigh 100 to 200 lbs.

The life expectancy is 7 to 13 years.

This dog will shed moderately year-round and perhaps more intensely seasonally.

He’s likely to inherit a strong prey drive from his Anatolian Shepherd side, so you’ll need to invest in impeccable recall training.

Basenji Great Dane Mix

Also known as: a Great Dasenji

The Great Dasenji has one Basenji parent and one Great Dane parent. This dog is likely to turn out smaller than many of the other mixes here.

The possible weight range is 22 to 190 lbs and the typical life expectancy is 7 to 14 years.

You may have light shedding, but coat care will be easy with this dog.

The Basenji is an ancient breed with more of a “cat-like” disposition and a strong chase drive, so this mix also demands rock-solid recall training!

Bloodhound Great Dane Mix

Also known as: a Great Hound

A Great Hound has one Bloodhound parent and one Great Dane parent.

This dog will usually weigh 100 to 200 lbs with a life expectancy of 7 to 12 years.

They tend to shed lightly year-round.

Your Great Hound will more than likely be great with kids but the famous Bloodhound scenting instinct means you might need to work hard at recall training!

Boxer Great Dane Mix

Also known as: a Boxane

The Boxane is a puppy with a Boxer parent and a Great Dane parent.

They can weigh 50 to 190 lbs with a life expectancy of 7 to 12 years.

Expect only light year-round shedding.

However, the Boxer is brachycephalic (flat-faced) which may present some health challenges, including respiratory, digestive, and eye issues.

Doberman Great Dane Mix

Also known as: Doberdane

When you cross a Doberman and a Great Dane, what you get is a Doberdane.

This dog may weigh 60 to 190 lbs with a life span of 7 to 12 years.

They will shed year-round but coat care is easy.

Expect a high-energy dog that is responsive to training, protective and people-oriented.

German Shepherd Great Dane Mix

Also known as: a Great Shepherd

Crossing a German Shepherd with a Great Dane produces a Great Shepherd puppy. This dog will weigh 50 to 190 lbs and live 7 to 10 years.

The Great Retriever will shed moderately year-round, especially seasonally.

Be aware, they will need plenty of exercising. They might also inherit cautiousness of strangers from their German Shepherd side. Lots of early socialisation will help with this.

Learn more by reading our full mix breed review here.

Golden Retriever Great Dane Mix

Also known as: a Great Retriever

The Great Retriever has one Golden Retriever parent and one Great Dane parent. Your dog will probably weigh between 55 to 190 lbs and have a lifespan of 7 to 12 years.

This dog is also likely to shed moderately year-round, and more heavily seasonally. Expect lots of personality and energy and a pooch that is highly people-centric.

Learn more by reading our full mix breed review here!

Great Pyrenees Great Dane Mix

Also known as: a Pyredane

A Pyredane has one Great Pyrenees parent and one Great Dane parent.

This dog will be sizeable, with a weight range of 85 to 190 lbs. The life expectancy is 7 to 12 years.

They will shed year-round as well as seasonally so expect lots of brushing duties!

Otherwise, you can expect an independent dog with a people-centric focus.

Greater Swiss Mountain Dog Great Dane Mix

Also known as: a Greater Swissdane

A Greater Swissdane is a puppy with a Greater Swiss Mountain dog parent and a Great Dane parent.

This will definitely be a big dog weighing somewhere in the range of 85 to 190 lbs. The typical lifespan is 7 to 11 years.

The Greater Swissdane will shed year-round as well as seasonally, but coat care duties will be fast and easy.

Be aware, they are quite strong and a tireless workers, who often have an independent streak. To give them a happy, fulfilling life (and stop them becoming bored and destructive) you’ll need to find ways to channel this work ethic.

Irish Wolfhound Great Dane Mix

Also known as: an Irish Dane

The Irish Dane is a cross between an Irish Wolfhound and a Great Dane.

One of the largest hybrid dogs, they will usually weigh 110 to 200+ lbs. Due to their size, their life expectancy is sadly short at 6 to 10 years.

This dog will shed mildly year-round.

In addition, the personality of this mix can be challenging in puppyhood because the Irish Wolfhound is notoriously slow to mature.

Labrador Retriever Great Dane Mix

Also known as: a Labradane

The popular Labradane has one Labrador Retriever parent and one Great Dane parent. This dog can weigh 55 to 190 lbs with a life expectancy of 7 to 12 years.

Expect a friendly, people-oriented pup that sheds all year long and seasonally.

Learn more by reading our full mix breed review here.

Mastiff Great Dane Mix

Also known as: a Daneiff

A Daneiff puppy has one Mastiff parent and one Great Dane parent.

This pooch can tip the scales at 110 to 230+ lbs. Because both parents are large breeds, their pup’s life expectancy is a brief 6 to 10 years.

They will shed year-round and seasonally. The Daneiff may inherit the Mastiff parent’s brachycephaly (flat face), which often produces respiratory and digestive issues.

Learn more by reading our full mix breed review here.

Poodle Great Dane Mix

Also known as: a Great Danoodle

The Great Danoodle is the name given to a puppy with a standard Poodle and a Great Dane for parents.

This dog will weigh between 40 and 190 lbs with a life span of 7 to 18 years.

They will only shed lightly, if at all, owing to the Poodle influence.

Learn more by reading our full mix breed review here.

Rottweiler Great Dane Mix

Also known as: a Weilerdane

The Weilerdane has one Rottweiler parent and one Great Dane parent.

They generally weigh 80 to 190 lbs with a life expectancy of 7 to 10 years.

This dog’s short coat is easy to brush but will shed moderately and perhaps seasonally.

Learn more by reading our full mix breed review here.

Saint Bernard Great Dane Mix

Also known as: a Saint Dane

A Saint Dane has one Saint Bernard parent and one Great Dane parent. They usually will weigh 120 to 190 lbs and live 7 to 10 years.

Expect moderate year-round and seasonal shedding (especially if the Saint Bernard parent is long-coated).

This dog is likely to be very good with kids and overall, extremely people-centric.

Siberian Husky Great Dane Mix

Also known as: a Great Danesky

The Great Danesky is a puppy with a Siberian Husky and a Great Dane for parents.

This dog will weigh 35 to 190 lbs with a lifespan of 7 to 14 years.

They tend to shed year-round and seasonally.

It’s likely they will inherit an independent yet sweet personality. Siberian Huskies are born and bred to run, so their puppies need excellent recall training to make sure they come back when you let them off leash.

Weimaraner Great Dane Mix

Also known as: a Weimar Dane

The Weimar Dane has one Weimaraner parent and one Great Dane parent.

They typically weigh 55 to 190 lbs and live 7 to 13 years.

This hybrid will probably shed lightly year-round.

Expect your Weimar Dane to need lots of daily exercising before they’re ready to relax at home!

Is a Great Dane Mix Right For Me?

We hope you have enjoyed learning about these unique Great Dane mix breed dogs!

But only you know whether one of these interesting and mixed breed dogs is the right pet for you.

If you have decided to take one of these unique gentle giants home, we’d love to hear all about it in the comments below.

References and Further Reading

Great Dane Club of America

American Pitbull Foundation

Great Dane Lovers Association of Western Australia

Bellumori T et al. 2013. Prevalence of inherited disorders among mixed-breed and purebred dogs. Journal of the American Veterinary Medical Association.